Dette studie fra USA blev stoppet før tid, da man allerede havde påvist effekten ved korsettering af skoliose, og dermed ikke kunne forsvare at have kontrolgruppen uden korset:
Weinstein SL, Dolan LA, Wright JG, Dobbs MB. Effects of Bracing in Adolescents with Idiopathic Scoliosis N Engl J Med. 2013 Oct 17;369(16):1512-21.
Udklip fra Resultaterne af studiet omkring bæretid på 12,9 timer/dag eller over for bedst effekt af korsettering:
BRACE DOSE–RESPONSE RELATIONSHIP
The majority of patients assigned to bracing (68%) were treated with a customized Boston-type thora- columbosacral orthosis. Temperature data were available for 116 patients (from both the random- ized and preference cohorts). During the first 6 months, patients wore the brace for a mean (±SD) of 12.1±6.5 hours per day (range, 0 to 23.0). The quartile of duration of brace wear was positively associated with the rate of success (P<0.001). The lowest quartile of wear (mean hours per day, 0 to 6.0) was associated with a success rate (41%) sim- ilar to that in the observation group in the pri- mary analysis (48%), whereas brace wear for an average of at least 12.9 hours per day was associated with success rates of 90 to 93% (Fig. 2).
Bracing significantly decreased the progression of high-risk curves to the threshold for surgery in patients with adolescent idiopathic scoliosis. The benefit increased with longer hours of brace wear.